Celiac disease test is useful if you often have diarrhea, swelling, and flatulence. If you have thought about trying gluten-free diet just to find out if your stomach problems are caused by celiac disease.
- Easy to use, non-invasive buccal genetic sample collector device, manufactured by Bode Technology.
- Safe and secure transport pouch with desiccant to protect and provide a stable environment for the sample during transport.
- Clear and easy to follow instructions on how to take the sample.
- Information about the test.
Celiac disease (also spelled as coeliac disease, sometimes referred to as sprue or gluten-sensitive enteropathy) is a chronic disorder caused by the body’s unusual reaction to gluten which results in the damage of the intestines and poor absorption in the guts (malabsorption).
Celiac disease is of autoimmune origin, meaning that the cells of the intestinal villi are damaged by the body’s own immune system and inflammatory reaction due to gluten intolerance, this protein is commonly found in wheat, rye and barley. When the mucous membranes and the cells are damaged, the villi of the small intestines become flat (villous atrophy) and the absorption of the nutrients such as vitamins, minerals and fats is decreased (malabsorption). Celiac disease has many faces, only a small proportion of individuals with celiac disease have classic symptoms, whereas a much bigger number of ill individuals have an atypical disease presentation. Furthermore, minimally active, completely asymptomatic disease (“silent celiac disease”) is observed in even greater number of persons.
Celiac disease is considered an autoimmune disorder triggered by the gluten intolerance, although the exact cause and mechanisms of the sprue haven’t been verified. It is suggested that the gluten intolerance seen in celiac disease is genetically predisposed with a strong association with human leukocyte antigen HLA-DQ2/DQ8. therefore, those who have a first-degree relative with celiac disease are at risk of developing celiac disease at some point in their life.
The consumption of gluten, namely, the reaction with gliadin, causes the inflammatory response mediated by the immune system and, probably, serum antibodies – IgA antigliadin, antiendomysial, and anti-tTG antibodies – are also involved.inflammation of the intestinal mucosa eventually leads to its atrophy, the number of mucous cells, intestinal villi and the depth of the crypts decrease gradually causing foods maldigestion and malabsorption of the nutrients.
Test Celiac disease with our DNA Celiac disease test.